The most important thing: THC inhibits CGRP release from trigeminal nerve endings – the same target as modern migraine biologics (Aimovig, Emgality). Rhyne 2016: Migraine frequency decreased from 10.4 to 4.6 attacks/month (-56 %). At a glance: THC inhibits CGRP – the same target as migraine biologics (Aimovig, Emgality) Rhyne 2016 (n=121): -56% migraine frequency […]