Most important: Dronabinol (synthetic THC) received FDA approval in 1985 for chemotherapy nausea – one of the oldest medical cannabis indications. CB1 in the vomiting center (area postrema) directly inhibits the serotonergic nausea signaling cascade. At a glance: Dronabinol FDA-approved for chemotherapy nausea since 1985 – one of the oldest cannabis indications CB1 in the […]