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Cannabis for bipolar disorder: risks, CBD & studies
in Cannabis, News/by StephanThe most important thing: THC is a recognized risk factor for mania triggers in bipolar disorder. 40% of bipolar patients use cannabis for self-medication – mostly for depressive phases. Psychiatric consultation is mandatory. At a glance: THC in bipolar disorder = risk factor for mania triggers – no attempt to self-medicate with THC 40% of […]
Cannabis for Alzheimer’s & dementia: CBD, neuroprotection & ECS
in Cannabis, News/by StephanMost importantly, Alzheimer’s patients have reduced anandamide levels and downregulated CB1 receptors in the entorhinal cortex. CBD inhibits amyloid-β aggregation and tau hyperphosphorylation – both core drivers of the disease. At a glance: CBD inhibits amyloid-β aggregation and tau hyperphosphorylation (in vitro and animal model) CB2 on microglial cells: Cannabis reduces neuroinflammation – a core […]
Cannabis for rheumatism & arthritis: CB2, inflammation & studies
in Cannabis, News/by StephanMost important: CB2 receptors are located directly on inflamed synovial cells and chondrocytes in rheumatism. Blake 2006 (RCT, n=58): Nabiximols significantly better than placebo for pain and disease activity (DAS28). At a glance: CB2 is directly expressed on synovial cells and chondrocytes – cannabis attacks at the site of inflammation Blake 2006 (RCT, n=58): Nabiximols […]
Cannabis for migraine: CB1, CGRP & studies
in Cannabis, News/by StephanThe most important thing: THC inhibits CGRP release from trigeminal nerve endings – the same target as modern migraine biologics (Aimovig, Emgality). Rhyne 2016: Migraine frequency decreased from 10.4 to 4.6 attacks/month (-56 %). At a glance: THC inhibits CGRP – the same target as migraine biologics (Aimovig, Emgality) Rhyne 2016 (n=121): -56% migraine frequency […]
Discover your own hoodie style! + 4 care basics
in Outfit/by F_kinskiThe hoodie has undergone an amazing development. It used to be practical work and sportswear – today it is one of the most popular fashion basics of all. Whether for everyday wear, university, the office or leisure: there are few items of clothing that are as comfortable, versatile and personal as a hoodie. And that’s […]
“Azzedine Alaïa’s Dior Collection” in Paris: the 101 looks that retell fashion history
in Designer, France, Travel/by F_kinskiParis has a new exhibition that is currently attracting fashion fans like magic: “Azzedine Alaïa’s Dior Collection”. Two designers, two worlds – and yet a perfect match. Anyone in Paris, whether on a short trip or a weekend tour, should not miss this show. It is already one of the most exciting fashion experiences of […]
Dassault Falcon 8X: Taylor Swift’s private jet series – range, price and facts
in News/by StephanDassault Aviation – it sounds like a fighter jet, and that is no coincidence. The French manufacturer originally developed military aircraft before applying its expertise to private aviation. The result: the Falcon series – aerodynamically brilliant, operationally efficient and unrivaled over long distances. The Dassault Falcon 8X is the flagship of this line, and Taylor […]
Social Clubs Spain: Buy legal cannabis on vacation – tips & list
in Cannabis, Spain, Travel/by F_kinskiSocial clubs in Spain are a discreet and relaxed way for many travelers, holidaymakers and patients to consume cannabis – away from street sales and without fear of legal consequences. In cities such as Barcelona, Madrid, Ibiza and Málaga, there are now numerous clubs that not only offer high-quality strains, but also a real lounge […]
Best Social Club Ibiza! Cannabis & Cappuccino in GREENtime Ibiza: 7 Island Tips
in Cannabis, Spain, Travel/by F_kinskiSocial Club in Ibiza – Imagine you are on a beautiful island in the Mediterranean Sea and you don’t have the same problems with cannabis as in other countries! Welcome to Ibiza. You are addicted to cannabis or marijuana? Then you shouldn’t ask on the street, but go specifically to a good social club. You […]
Social Clubs Madrid: Buy cannabis, weed, legally in the capital
in Cannabis, Spain, Travel/by F_kinskiAre you planning a trip to Madrid and want to know how the local social clubs work? Then you’ve come to the right place. Madrid is home to some of the most exciting cannabis social clubs in Spain – from Green Paradise to Euphoria. We visited them, shot videos and show you our recommendations here. […]