Entries by Stephan

Rolex Submariner: Prices, models & buying advice

The Rolex Submariner is the best-selling luxury watch in the world – and has been for over 70 years. It is not just a timepiece, but a status symbol, a collector’s item and an investment. What makes it so special, what does it really cost – and how can you recognize a fake? The article […]

Egypt vacation: tips for Cairo, Luxor and the Red Sea

Egypt is one of the most fascinating travel destinations in the world – nowhere else do thousands of years of history, breathtaking natural landscapes and vibrant city life come together in such a small space. Whether pyramids, Nile cruise or diving in the Red Sea: Egypt surprises anew on every trip. When planning your trip, […]

Hyaluronic serum: effect, application and the best products

Hyaluronic serum is the best-selling skin care product in the world – and for good reason. Hyaluronic acid binds up to 1,000 times its own weight in water and plumps up the skin from the inside. If you don’t yet have a serum in your daily routine, you are missing out on real potential. What […]

By private jet to Nice, Monaco and Cannes – traveling to the Cote d’Azur

There are destinations that are so inextricably linked to a certain lifestyle that the journey itself becomes a statement. The Côte d’Azur – Nice, Monaco and Cannes – is one such destination. Here, where the Alps meet the Mediterranean, life pulsates between superyacht harbors, film festivals and casino nights. The jet set on the Côte […]

Cannabis for back pain: CBD, THC & intervertebral discs

The most important thing: Chronic back pain has four types of pain (nociceptive, neuropathic, myofascial, centralized) – cannabis attacks all four at the same time. 70% of patients report a strong reduction. And: cannabis can reduce opioid requirements by 44 %. At a glance: Cannabis simultaneously targets all 4 types of pain: nociceptive, neuropathic, myofascial, […]

Layered look: layering like a pro – the best styling tips

The layered look is more than just a trend – it’s a style philosophy. Wearing several layers on top of each other sounds like too much at first, but if you master the art of layering, you will never look overloaded, but rather well thought-out and individual. The basis for every layered look is a […]

Cannabis for social anxiety: CBD & social phobia

Most importantly, social anxiety is the best clinically proven cannabis indication. Bergamaschi 2011 (RCT): CBD 600 mg measurably halved anxiety, cognitive impairment and physiological stress during public speaking. THC, on the other hand, can increase social anxiety. At a glance: Bergamaschi 2011 (RCT): CBD 600 mg halved anxiety, cognitive impairment and stress Optimal dose: 300 […]

Cannabis for Crohn’s disease: CBD, remission & studies

Most important: Naftali 2013 – the first RCT on cannabis in Crohn’s disease – showed 45% full remission with THC cannabis versus 10% placebo. CBD alone was not sufficient for remission induction. THC component is crucial for Crohn’s disease. At a glance: Naftali 2013 (RCT): 45 % full remission with cannabis vs. 10 % placebo […]

Cannabis for restless legs: CBD, dopamine & studies

The most important thing: Restless legs syndrome (RLS) affects 5-10% of the population and is often resistant to treatment. Cannabis intervenes directly in RLS pathophysiology via dopaminergic modulation (CB1 in basal ganglia) and spinal pain processing (TRPV1). At a glance: RLS affects 5-10% of the population and is treatment-resistant in many cases Ghorayeb 2020: 6 […]

Cannabis & bones: CB2, osteoporosis & bone healing

The most important thing: CB2 receptors – the non-psychoactive cannabinoid receptor class – are located directly on osteoblasts and osteoclasts. CB2 activation promotes bone formation and inhibits bone resorption. CBD significantly accelerated fracture healing in animal models. At a glance: CB2 receptors are located directly on osteoblasts (bone formation) and osteoclasts (bone resorption) CB2 knockout […]